Breast Cancer and Cell Biology

Cancer cells are very complex cells and it is challenging for clinicians to manage breast cancer therapy. Tumor cells are having different phenotypes and deregulated apoptotic and these characteristics are responsible for improper therapeutic response. For multidrug resistance events major role is played by membrane transporters, they are the cell’s first line of contact with anticancer drugs. So cell structure and biological properties of the cell lead to drug-resistance and a decrease in the intracellular activity of drugs. Breast growth is regulated by the interaction between hormones and growth factors. Genetic changes in growth factor can lead to abnormalities. The immune system of host play a substantial role during breast cancer, breast cancer is a complex disease.


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