Immunotherapy in Breast Cancer

Immunotherapy has emerged as one of the most transformative approaches in oncology, and its application in breast cancer is opening new avenues for patient care, especially in aggressive and treatment-resistant subtypes. This session will explore the evolving role of immunotherapeutic strategies in breast cancer, including checkpoint inhibitors, cancer vaccines, and adoptive cell therapies. Unlike more immunogenic tumors such as melanoma or non-small cell lung cancer, breast cancer has traditionally been considered immunologically "cold." However, recent studies have shown that certain subtypes, particularly triple-negative breast cancer (TNBC), may respond favorably to immunotherapeutic agents when combined with conventional therapies like chemotherapy. This session will highlight the mechanisms by which breast tumors evade immune surveillance and how new treatments are being designed to counteract these processes. Clinical trial data will be presented to assess the efficacy and safety of these agents in both early-stage and metastatic breast cancer settings.

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